Patient Counseling Points for Sildenafil Citrate Therapy

Other side effects include a drop in blood pressure, insomnia, nasal congestion, or a runny nose and nosebleeds. Sudden hearing loss has also been reported. Some people taking sildenafil have had bleeding events; however, it has not been established if this is related to sildenafil use.

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Under the Rules of Origin the original foreign country of origin would remain. Animal, Plant, Fish) may require special country importation requirements.USP recommends you contact your country competent authorities to determine if any certifications, permits or licenses may be required prior to ordering.Material Origins are found within the Product under Origin Information. Sildenafil is used to treat erectile dysfunction (ED) in men or pulmonary arterial hypertension (PAH) in both men and women, depending on the brand. Viagra and Vybrique are used for ED and Revatio is used for PAH. Sildenafil works by blocking the action of an enzyme called lovegra sildenafil cGMP-specific phosphodiesterase type-5 (PDE-5).

Who can use Sildenafil Citrate Tablets?

This enzyme breaks down cGMP, a substance that induces smooth muscles to relax. Blocking PDE-5 means increased levels of cGMP within the smooth muscles which promotes muscle relaxation and vasodilation (a widening of blood vessels). High levels of PDE-5 are found in the penis, lungs, and retina. PDE-5 is also found throughout the body within the smooth muscle cells of the blood vessels and muscles. Sildenafil belongs to the drug class called phosphodiesterase (PDE) type 5 inhibitors.

Dosage for erectile dysfunction (ED)

Sildenafil (Viagra, Vybrique brands and generic) is used to treat erectile dysfunction (ED, impotence). It increases blood flow to the penis following sexual stimulation by blocking the enzyme responsible for the breakdown of cGMP. This allows men to keep an erection hard enough for sex. Sildenafil (Viagra, Vybrique brands and generic) only works following sexual stimulation. It works within 30 to 60 minutes, but may be taken up to four hours before sexual activity. Rarely, may decrease blood flow to the optic nerve causing sudden vision loss.

The risk is greater in people aged older than 50, with diabetes, heart disease, high blood pressure, high cholesterol, who smoke, or with certain pre-existing eye problems.

Rarely, may cause other side effects or lead to painful erections lasting longer than four hours.

Overdose/Missed Dose

If you are taking Revatio and you forget to take your scheduled dose, take it as soon as possible. However, you should never double your dosage. If you completely miss a dose and it’s time for the next dose, skip the one you missed. Are there any safety measures I should take before using this drug? Like most medications, there are precautions you should take before using this drug.

Related treatment guides

Make sure you talk with your doctor about: any other drugs, medications, herbs, or supplements you take or plan to take any medical conditions or surgeries you have or plan to have if you are pregnant or plan to become pregnant There are other drugs available to treat your condition. Some may be better suited for you than others. Talk with your doctor about other drug options that may work for you. Sildenafil and tadalafil are alike because they both can treat ED and PAH. However, tadalafil has a few distinctions from sildenafil.

Postmarketing Reports

Tadalafil is the generic name for the erectile dysfunction drug Cialis. There are two versions of the drug: a version that can be taken as needed Cialis 5-mg daily dosing is the only PDE5 inhibitor dose approved for treating an enlarged prostate; improving ED symptoms is an added benefit of the daily dose. Because of the “as needed” version of tadalafil, some users may find this option more convenient. The downside, however, is that side effects tend to last longer too. The main difference between generic sildenafil and Viagra is marketing. See your doctor immediately if this happens. May not be suitable for some people including those with angina, chest pain, other heart conditions, liver or kidney problems, blood or bleeding disorders, stomach ulcers, certain eye conditions, or a physical deformity of the penis (such as Peyronie's disease). Higher dosages of sildenafil are associated with a higher risk of death in children with PAH.

Mechanism of action

Your doctor will write the number of refills authorized on your prescription. When flying, never put it into a checked bag. Keep it in your carry-on bag. Don’t worry about airport X-ray machines. You may need to show airport staff the pharmacy label for your medication.

Stop smoking and avoid alcohol

Always carry the original prescription-labeled container with you. Don’t put this medication in your car’s glove compartment or leave it in the car. Be sure to avoid doing this when the weather is very hot or very cold. If you’re taking this drug for PAH, your doctor may monitor your blood pressure and pulse regularly. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.

Product Name

Many insurance companies require prior authorization for this drug. This means your doctor may need to get approval from your insurance company before your insurance company will pay for the prescription. Sildenafil under the brand name Viagra is prescribed to treat erectile dysfunction by increasing blood flow to the penis during arousal. Sildenafil under the brand name Revatio is often prescribed to help adults with PAH get more exercise by treating their condition. What if I forget to take it? For this reason, the FDA does not recommend use in children aged less than 18 years. May interact with some medications including certain antibiotics and antifungals, herbal remedies, HIV medicines, nitrates, and drugs used in the treatment of high blood pressure or prostate disorders.

• Sildenafil citrate can be combined with lifestyle changes.
• Exercise and weight management improve erectile function.
• Quitting smoking enhances medication effectiveness.
• Reducing alcohol intake minimizes side effects.
• Psychological therapy may support ED treatment.
• Counseling can address underlying emotional issues.
• Regular medical check-ups are recommended.
• Patient education improves safe and effective use.

Sildenafil should not be taken with other PDE-5 inhibitors. The dosage may need to be reduced in people with kidney or liver disease.

Further information

The main ingredient in Viagra is sildenafil, meaning that the drugs are essentially the same. However, Viagra is marketed and prescribed strictly for erectile dysfunction, while generic sildenafil can be prescribed for PAH as well. Viagra is also known as “the little blue pill” because of its blue color, while generic sildenafil tends to be a white color. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional.

Less common

You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. USP Certificates/Product Information Sheets and Valid Use Dates View the USP Certificate or Product Information Sheet in the table above to view additional product details, including available label text and storage information. View the USP Certificate or Product Information Sheet in the table above to view additional product details, including available label text and storage information.

Liens externes

1The Harmonized System (HS) code provided on this webpage is for informational purposes only and is subject to change without notice. The exporter and/or importer of record is responsible for determining the accuracy of items at the time of export/import per U.S. regulations. USP is not responsible for the accuracy or completeness of the information furnished. 2USP procures materials worldwide and most foreign materials do not undergo a fundamental change during the packaging process at USP that would substantially transform the item resulting in a country of origin change from the foreign origin to the United States. More research is needed to establish if sildenafil has a role in sexual dysfunction in women. Sildenafil offers no protection against sexually transmitted diseases. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. Sildenafil is used to treat erectile dysfunction (ED) (Viagra, Vybrique brands, generic) and to reduce blood pressure in pulmonary arterial hypertension (PAH) (Revatio brand). It is taken when needed for ED approximately 1 hour before sexual stimulation (maximum dose once daily) and daily for PAH. A headache, stomach upsets, and flushing are the main side effects, and it should not be taken within 24 hours of a nitrate. If you are taking sildenafil (Viagra, Vybrique) for ED, do not take it more than once a day.

7. Interactions

Sildenafil (Revatio brand) reduces high blood pressure associated with pulmonary arterial hypertension (PAH). This improves the ability to exercise in people with PAH and delays any worsening of their symptoms. When used to treat PAH, sildenafil is available as tablets (20 mg) for and an IV injection. When used for ED, sildenafil is available as oral tablets of 25 mg, 50 mg, and 100 mg strengths, or an oral film (Vybrique brand) of 25 mg, 50 mg, 75 mg, and 100 mg strengths. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Dyspepsia, flushing, headache, indigestion, muscle or back pain, and visual disturbances are the most common side effects reported. Take an hour before sexual stimulation (range 30 minutes to 4 hours). If you take it with a high-fat meal it may delay how quickly it starts working.

• The discovery of sildenafil began with research on heart drugs.
• It was found to cause vasodilation as a side effect.
• Pfizer refined the drug for erectile dysfunction.
• It became a blockbuster drug upon FDA approval.
• Sildenafil has helped millions worldwide.
• It has changed perceptions about male sexual health.
• Ongoing research explores new formulations.
• Awareness campaigns promote safe usage.

Place sildenafil film on your tongue and allow it to dissolve. If you are taking sildenafil (Revatio) for PAH, take it as directed (the usual dosage is three times daily).

• Sildenafil molecules work by relaxing smooth muscle tissue.
• This relaxation allows increased blood flow in blood vessels.
• It is less effective without sexual arousal.
• Some common brand names include Viagra, Revatio, and Kamagra.
• Sildenafil's patent expired, leading to numerous generics.
• Generic versions are usually more affordable.
• It’s important to follow prescription instructions strictly.
• Using more than the recommended dose can be dangerous.

You can take it either with or without food. Do not consume grapefruit or grapefruit products while taking sildenafil.