Fear of sexual intercourse or intimacy (genophobia). Conditions that affect your body’s ability to deliver blood to your penis are the most common cause of ED.

Interacting Drug/Class Effect on ED Medication Clinical Concern Recommended Action
Nitrates Potentiate hypotension Risk of dangerous blood pressure drop Avoid concurrent use
Alpha-blockers Additive blood pressure lowering Dizziness, fainting Dose adjustment, monitoring
CYP3A4 inhibitors Increase ED medication levels Increased side effects Dose reduction, careful monitoring
Grapefruit juice Inhibits CYP3A4 enzyme Raises drug plasma levels Avoid consuming with ED meds

You may have a greater risk of getting ED if you: Have a body mass index (BMI) over 25. A healthcare provider can diagnose ED and determine its cause. They’ll review your medical history and perform a physical exam. They’ll also ask you questions about your personal and sexual history.

  • Cultural Attitudes: Vary significantly across different societies and age groups.
  • Media Influence: Direct-to-consumer advertising has increased awareness.
  • Open Discussion: Becoming less taboo, encouraging men to seek help.
  • Aging Population: Increasing prevalence as the global population ages.
  • Economic Impact: A multi-billion dollar global market for medications.
  • Accessibility: Still a major issue in many developing countries.
  • Educational Efforts: Campaigns by healthcare providers to reduce stigma.

These questions may make you feel embarrassed or awkward. But it’s important to be honest with the provider in order to quickly determine the cause. Are you currently taking any medications, including prescription drugs, over-the-counter drugs, herbal supplements, dietary supplements and nonmedical drugs? Has a healthcare provider ever diagnosed you with depression or anxiety? How often are you able to get erections?

  • Insurance Preauthorization: Often required for brand-name medications.
  • Step Therapy: May require trying generics before brand names are covered.
  • Medicare: Part D plans typically cover generic ED medications.
  • Medicaid: Coverage varies significantly from state to state.
  • Out-of-Pocket Cost: For uninsured or if medication is not covered.
  • Coupons and Savings Cards: Often available from manufacturers for brand drugs.
  • Pharmacy Choice: Costs can vary between different pharmacy retailers.

How long are you able to maintain an erection? Do you lose your erection because you ejaculate sooner than you would like? When did you first notice symptoms of erectile dysfunction? What exactly happened when you first had erectile dysfunction symptoms?

Brand Name Generic Name Dosage Forms Mode of Action Typical Dosage
Viagra Sildenafil Citrate Tablets Vasodilation via PDE5 inhibition 50-100 mg as needed
Cialis Tadalafil Tablets Long-lasting PDE5 inhibitor 10-20 mg as needed
Levitra Vardenafil Tablets PDE5 inhibition 10-20 mg as needed
Stendra Avanafil Tablets Rapid onset PDE5 inhibitor 50-200 mg as needed

Do or did you experience erections at night or during the morning? What sexual positions do you regularly engage in? The provider may also ask to talk with your sexual partner. Your partner may be able to offer additional insight on potential causes. The provider may order tests to confirm their diagnosis and determine the cause of your ED. It depends on what your healthcare provider suspects is causing erectile dysfunction. Tests that measure if the nerves in your penis respond to vibrations (penile biothesiometry). Drugs that temporarily make your penis erect (vasoactive injection). Before testing, your provider will explain what’s involved with a test and answer any questions you have. If you don’t feel comfortable, you can decide not to do the test at any time. The first step in treating erectile dysfunction is identifying the underlying cause. A healthcare provider will help determine the best treatment for you.

What Our Patients Say

Erectile dysfunction is the most common sex-related condition that males report to healthcare providers, especially as they age and develop other health issues. Providers and medical researchers estimate that erectile dysfunction affects over 50% of males between the ages of 40 and 70. And those numbers may be higher — many don’t seek help for the condition due to embarrassment or shame. Only sometimes being able to get an erection before sexual intercourse. Being able to get an erection before sexual intercourse but not being able to maintain it during sexual intercourse.

Watch out for side effects

Requiring a lot of stimulation to maintain an erection. There are many possible causes of ED, including conditions that affect your: Your circulatory system includes the blood vessels that carry blood throughout your body. Your penis needs adequate blood flow to become erect and maintain an erection. Your penis also relies on a series of valves to close when it fills with blood — in some cases, these valves stop working as they should. Your nervous cenforce 100 uk system includes your brain, spinal cord and nerves. Vigorous cardiovascular exercise for at least 45 minutes three times per week may help reverse some cases of mild ED. Cardiovascular exercises may include brisk walking, jogging, swimming, bicycling and jumping rope. For men with mild ED, quitting smoking can lead to improvement after several months. Oral medications that help increase blood flow to your penis, including sildenafil (Viagra®), vardenafil (Levitra®), tadalafil (Cialis®) or avanafil (Stendra®).

Product Dosage Quantity + Bonus Price
Kamagra Oral Jelly100mg21 Sachets95.92€ 91.35€
Kamagra Soft Tabs100mg120 + 6 Pills311.78€ 296.93€
Cialis Generic60mg30 + 2 Pills85.33€ 81.27€
Kamagra Effervescent Tablets100 mg63 + 7 Pills171.99€ 163.80€
Cialis Generic20mg120 + 8 Pills188.15€ 179.19€
Cialis Original20mg64 + 4 Pills274.18€ 261.12€
Kamagra Gold100 mg60 + 4 Pills201.34€ 191.75€
Cialis Generic5mg270 + 10 Pills205.81€ 196.01€
Cialis Generic20mg360 + 10 Pills427.34€ 406.99€
Cialis Black80mg10 Pills43.27€ 41.21€
Kamagra Gold100 mg360 + 6 Pills839.95€ 799.95€
Viagra Generic200mg120 + 8 Pills204.80€ 195.05€
Levitra Generic20mg10 Pills31.49€ 29.99€
Viagra Professional100mg120 + 4 Pills262.83€ 250.31€
Cialis Generic10mg270 + 10 Pills308.71€ 294.01€

Oral medications start to work within an hour. Penile low-intensity focused shockwave therapy (LiSWT). This noninvasive treatment improves blood flow by using sound waves. It can take two months to see improvement. Medications sex power tablet you inject directly into your penis to create an erection, including alprostadil (Caverject®), papaverine (Papacon®), phentolamine (Regitine®) or a combination of multiple medications. Injectable medications start to work within 10 minutes. Penis pumps start to work almost immediately. Testosterone replacement therapy, which is available as a gel, injection, patches and pellets. Testosterone replacement therapy starts to work within four weeks. A penile implant is a procedure in which a surgeon places a device into your penis to make it hard. The device doesn’t affect sensation, peeing or orgasm.

How do ED drugs work?

They work together to send electrical impulses that help your body move and feel, including your penis. Your endocrine system includes the glands that create and release hormones. Hormones help tell your body to perform certain functions. Testosterone may help open up (vasodilate) your blood vessels, which helps blood flow to your penis. Injuries (trauma) to your penis and surrounding areas can also cause ED.

1. VED (Vacuum Erection Device)

Injuries to your pelvis bones (hip bones, sacrum and tailbone), bladder, prostate and spinal cord. Pelvic surgery, including prostate, colon or bladder cancer surgery. Erectile dysfunction is a common side effect of many prescription drugs. Common medications that list ED as a potential side effect include: Substances that have addiction potential may cause ED, including: These substances can affect and suppress your central nervous system. They can also cause severe damage to your blood vessels, which may lead to permanent erectile dysfunction. ED will not likely go away on its own without changes to your lifestyle or some kind of treatment. The outlook for ED is good and it’s a very treatable condition. Though there aren’t cures for some causes of ED, many treatment options can help you get and maintain an erection hard enough for sexual intercourse. Certain lifestyle changes can help lower your risk of developing erectile dysfunction, including: Being more physically active, especially doing cardiovascular exercises like running, jogging or bicycling. Eating healthy foods with low saturated fats, such as fruits, vegetables and whole grains. Talk to a primary care physician or a urologist if you suspect you have erectile dysfunction. They can help diagnose ED, identify its cause and recommend the best treatment option for you. A urologist is a healthcare provider who specializes in diagnosing and treating conditions that affect your reproductive system and urinary system. Go to your nearest emergency room if you’re taking medication for erectile dysfunction and have a painful erection that lasts longer than two to four hours. This may be a sign of priapism, which can cause permanent damage to your penis without treatment.

We're here for you

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Erectile dysfunction (ED) is a type of penile disorder. It affects your ability to get and maintain an erection firm enough for sexual intercourse.

Vitamins and supplements for ED

Your feelings play a major role in getting and maintaining an erection. Feeling relaxed, confident and aroused is essential. But it’s normal to sometimes have erection issues. Erection problems can occur if you feel nervous, anxious, frustrated or tired. Drinking alcohol and/or using substances can also have an effect. Is it normal to have erectile dysfunction? How do you know I have erectile dysfunction? What ED treatment option do you recommend? Can erectile dysfunction cause other conditions that affect my sexual health? Can you recommend a support group for people who have erectile dysfunction? Am I a candidate for a penile implant procedure?

Treatment Type Method Description Advantages Limitations
Vacuum Erection Devices Mechanical pumps to induce erection Non-invasive, drug-free Temporary effect, discomfort
Penile Implants Surgical placement of prosthetic devices Permanent solution Surgery risks, cost
Pelvic Floor Exercises Kegel exercises to strengthen pelvic muscles Improves erectile function over time Requires consistency
Counseling and Therapy Psychological support for ED causes Addresses underlying issues Time-consuming, variable results

Erectile dysfunction can cause you to feel many different emotions. You may feel embarrassed, frustrated, guilty, ashamed, angry or “less than.” This can lead to more serious long-term emotions, like anxiety and depression. But you don’t have to live with these feelings. ED is common, and it doesn’t reflect your worth as a person. Erectile dysfunction is a sensitive topic for many people. The following tips can help you support your partner if they have erectile dysfunction: Tell your partner you care about their feelings and well-being. Find appropriate times to talk to your partner that won’t make them feel vulnerable. Remind your partner that they’re not alone. ED is common, and treatment is available. Therapists and support groups can help your partner process their feelings. Focus on the benefits of regular exercise, healthy foods and cutting back on substances that may cause ED. Your partner will feel supported if you have accurate, up-to-date information on erectile dysfunction and its treatment options.

Myth 3: If one ED medication doesn’t work, none of them will.

It can also result from other conditions or as a side effect of certain medications or cancer treatments. If you’re having difficulty getting or maintaining an erection, it’s a good idea to schedule an appointment with a healthcare provider for further discussion. In many cases, ED can be the first symptom of another underlying problem, including heart disease. It’s important to talk to a healthcare provider if you have problems getting and maintaining an erection. Healthcare providers separate ED into several categories: Vascular ED includes causes that affect the blood vessels that send blood to the tissues in your penis that allow you to get and maintain an erection, or the valves in the penis that normally hold blood inside.

3. Urethral suppository

Vascular ED is the most common type of ED. Neurogenic ED occurs as a result of nerve problems, which prevent signals from traveling from your brain to your penis to create an erection. This can happen because of trauma, pelvic surgery, radiation therapy or neurologic conditions like stroke, spinal stenosis and multiple sclerosis (MS). Hormonal ED refers to ED that happens as a result of testosterone deficiency, or in some cases as a result of thyroid issues. Psychogenic ED involves psychological conditions (conditions that affect your thoughts, feelings or behavior) that can cause ED. Offer to go with your partner to their appointments. You can help your partner ask questions, take notes and relay information to a healthcare provider that can help them in making a diagnosis.